Supplementary information

Overview on additional supplementary information for the manuscript "Integrating scientific considerations into R&D project valuation" by de Visser et al.

Animation explaining NPV and rNPV

A short animation explaining Net Present Value (NPV) and risk-adjusted NPV (rNPV) approaches for the development of an hypothetic medical device.

 

Question Optimizing Calculator

A user-friendly tool which calculates the most optimal development route for a new medical intervention given estimates for success rates, costs, future profits and or 5-6 key scientific questions.

 

Question Optimizing Calculator – tutorial

A brief tutorial explaining the Question Optimizing Calculator and its output files.

Downloads

This tool is part of the course Clinical Development

The Question Optimizing Calculator is part of the blended course Clinical Development and has been used by more than 150 course participants from around the world who are working on the development of new medical interventions in academia and industry. The blended course offers thorough understanding of the Question Based Clinical Development approach and a practical understanding of how to apply the concepts by analyzing the successes and failures of real R&D projects from academia and industry.

Paul Janssen Futurelab
Paul Janssen Futurelab